Studies

S10

SAFETY AND EFFICACY

Scalp cooling is an increasingly recognized non-pharmacologic approach to minimize chemotherapy-induced alopecia (CIA). This study was a single-institution review of outcomes from manual cold capping.

Retrospective evaluation of Penguin Cold Caps for chemotherapy-induced alopecia

S10

Efficacy

Scalp cooling with cold caps appears to be effective in preventing CIA among the majority of women undergoing treatment with TC chemotherapy

Efficacy of Scalp Cooling in Preventing Chemotherapy-Induced Alopecia in Breast Cancer Patients Receiving Adjuvant Docetaxel and Cyclophosphamide Chemotherapy

S10

Efficacy

The efficacy of scalp hypothermia (Penguin Cold Caps) in the prevention of alopecia, which is frequently seen due to chemotherapy, has been evaluated

S10

SAFETY

The incidence of scalp metastases was low regardless of scalp cooling. This analysis suggests that scalp cooling does not increase the incidence of scalp metastases.

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis

Scalp hypothermia with Penguin is effective in reducing alopecia, particularly for non-anthracycline-based shorter regimens.
Penguin was well tolerated and viewed favorably by most patients.

Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy

S10

EFFICACY

The use of a scalp-cooling device prevented alopecia with acceptable safety. In addition, scalp cooling resulted in faster recovery of hair volume after chemotherapy, even in patients for whom scalp cooling failed to prevent chemotherapy-induced alopecia

Efficacy of Scalp Cooling: The Hope Study

S10

EFFICACY

Patients feel better overall about their experience because they’ve been able to control one aspect of their treatment. Even patients who lose a substantial amount of hair are pleased that they used the device, and many notice that their hair is growing back while chemotherapy is still under way

Real-World Use of Scalp Cooling to Reduce Chemotherapy-Related Hair Loss

S10

EFFICACY

Scalp cooling was found to be effective for hair preservation in some patients on chemotherapy
especially with taxanes. The scalp cooling
sessions were also well tolerated without any serious adverse events by the end of the study

S10

SAFETY

Scalp cooling does not appear to increase the risk of cutaneous scalp metastases in early-stage breast cancer patients, nor does it appear to compromise cancer outcome

Scalp cooling to prevent chemotherapy-induced alopecia

S10

SAFETY

Scalp metastasis and scalp cooling discontinuation was observed to be very rare

Safety and efficacy of scalp cooling system in preventing chemotherapy induced alopecia - A single center prospective study

S10

EFFICACY

The current meta-analysis suggests that in female patients with breast cancer, the use of scalp cooling, compared to no scalp cooling, reduces the risk of significant hair loss

Efficacy of scalp cooling for prevention of chemotherapy induced alopecia: a systematic review and meta-analysis

Cooling system was associated with a lower risk of hair loss among women receiving non–anthracycline-based chemotherapy for early-stage breast cancer.

Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer

S10

EFFICACY

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients

Scalp cooling resulted in faster recovery of hair volume after chemotherapy

S10

EFFICACY

Scalp cooling is an approved and generally well-tolerated option to prevent CIA and can minimize the burden of cancer treatment and potential impairments in patients’ health-related quality of life and psychosocial well-being

Scalp cooling to prevent chemotherapy-induced alopecia

S10

SAFETY

Scalp metastases: the incidence is so low in women with breast cancer that scalp cooling can be provided without the risk of this rare occurrence

Scalp Cooling: The Prevention of Chemotherapy-Induced Alopecia

Evidence-Based Success: Clinical Studies on Scalp Cooling

Scalp cooling is an increasingly recognized non-pharmacologic approach to minimize chemotherapy-induced alopecia (CIA). This study was a single-institution review of outcomes from manual cold capping.

Scalp cooling with cold caps appears to be effective in preventing CIA among the majority of women undergoing treatment with TC chemotherapy

The efficacy of scalp hypothermia (Penguin Cold Caps) in the prevention of alopecia, which is frequently seen due to chemotherapy, has been evaluated

The incidence of scalp metastases was low regardless of scalp cooling. This analysis suggests that scalp cooling does not increase the incidence of scalp metastases.

Scalp hypothermia with Penguin is effective in reducing alopecia, particularly for non-anthracycline-based shorter regimens.
Penguin was well tolerated and viewed favorably by most patients.

The use of a scalp-cooling device prevented alopecia with acceptable safety. In addition, scalp cooling resulted in faster recovery of hair volume after chemotherapy, even in patients for whom scalp cooling failed to prevent chemotherapy-induced alopecia

Patients feel better overall about their experience because they’ve been able to control one aspect of their treatment. Even patients who lose a substantial amount of hair are pleased that they used the device, and many notice that their hair is growing back while chemotherapy is still under way

Scalp cooling was found to be effective for hair preservation in some patients on chemotherapy
especially with taxanes. The scalp cooling
sessions were also well tolerated without any serious adverse events by the end of the study

Scalp cooling does not appear to increase the risk of cutaneous scalp metastases in early-stage breast cancer patients, nor does it appear to compromise cancer outcome

Scalp metastasis and scalp cooling discontinuation was observed to be very rare

The current meta-analysis suggests that in female patients with breast cancer, the use of scalp cooling, compared to no scalp cooling, reduces the risk of significant hair loss

Cooling system was associated with a lower risk of hair loss among women receiving non–anthracycline-based chemotherapy for early-stage breast cancer.

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients

Scalp cooling is an approved and generally well-tolerated option to prevent CIA and can minimize the burden of cancer treatment and potential impairments in patients’ health-related quality of life and psychosocial well-being

Scalp metastases: the incidence is so low in women with breast cancer that scalp cooling can be provided without the risk of this rare occurrence

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Evidence-Based Success: Clinical Studies on Scalp Cooling

Scalp cooling is an increasingly recognized non-pharmacologic approach to minimize chemotherapy-induced alopecia (CIA). This study was a single-institution review of outcomes from manual cold capping.

Scalp cooling with cold caps appears to be effective in preventing CIA among the majority of women undergoing treatment with TC chemotherapy

The efficacy of scalp hypothermia (Penguin Cold Caps) in the prevention of alopecia, which is frequently seen due to chemotherapy, has been evaluated

The incidence of scalp metastases was low regardless of scalp cooling. This analysis suggests that scalp cooling does not increase the incidence of scalp metastases.

Scalp hypothermia with Penguin is effective in reducing alopecia, particularly for non-anthracycline-based shorter regimens. ​Penguin was well tolerated and viewed favorably by most patients.

The use of a scalp-cooling device prevented alopecia with acceptable safety. In addition, scalp cooling resulted in faster recovery of hair volume after chemotherapy, even in patients for whom scalp cooling failed to prevent chemotherapy-induced alopecia

Patients feel better overall about their experience because they’ve been able to control one aspect of their treatment. Even patients who lose a substantial amount of hair are pleased that they used the device, and many notice that their hair is growing back while chemotherapy is still under way

Scalp cooling was found to be effective for hair preservation in some patients on chemotherapy especially with taxanes. The scalp coolingsessions were also well tolerated without any serious adverse events by the end of the study

Scalp cooling does not appear to increase the risk of cutaneous scalp metastases in early-stage breast cancer patients, nor does it appear to compromise cancer outcome

Scalp metastasis and scalp cooling discontinuation was observed to be very rare

The current meta-analysis suggests that in female patients with breast cancer, the use of scalp cooling, compared to no scalp cooling, reduces the risk of significant hair loss

Cooling system was associated with a lower risk of hair loss among women receiving non–anthracycline-based chemotherapy for early-stage breast cancer.

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients

Scalp cooling is an approved and generally well-tolerated option to prevent CIA and can minimize the burden of cancer treatment and potential impairments in patients’ health-related quality of life and psychosocial well-being

Scalp metastases: ​the incidence is so low in women with breast cancer that scalp cooling can be provided without the risk of this rare occurrence​

Need More Information?

Scalp hypothermia with Penguin is effective in reducing alopecia, particularly for non-anthracycline-based shorter regimens.
Penguin was well tolerated and viewed favorably by most patients.

Scalp cooling was found to be effective for hair preservation in some patients on chemotherapy
especially with taxanes. The scalp cooling
sessions were also well tolerated without any serious adverse events by the end of the study

Scalp metastases: the incidence is so low in women with breast cancer that scalp cooling can be provided without the risk of this rare occurrence